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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1B
All Species:
0
Human Site:
Y257
Identified Species:
0
UniProt:
O75688
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75688
NP_002697.1
479
52643
Y257
S
N
E
E
L
C
E
Y
V
K
S
R
L
E
V
Chimpanzee
Pan troglodytes
XP_001167412
430
48336
I223
N
P
L
E
K
E
R
I
Q
N
A
G
G
S
V
Rhesus Macaque
Macaca mulatta
XP_001111662
479
52622
F257
S
N
E
E
L
C
E
F
V
K
S
R
L
E
V
Dog
Lupus familis
XP_851683
479
52774
F257
S
N
E
E
L
C
E
F
V
K
S
R
L
E
V
Cat
Felis silvestris
Mouse
Mus musculus
P36993
390
42776
A183
E
K
E
R
I
Q
N
A
G
G
S
V
M
I
Q
Rat
Rattus norvegicus
P35815
390
42871
A183
E
K
E
R
I
Q
N
A
G
G
S
V
M
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512797
382
42443
I175
N
P
L
E
K
E
R
I
Q
N
A
G
G
S
V
Chicken
Gallus gallus
NP_001026223
387
42716
I180
N
P
R
E
K
E
R
I
Q
N
A
G
G
S
V
Frog
Xenopus laevis
NP_001085063
455
50420
G244
F
I
I
L
A
C
D
G
I
W
D
V
M
S
N
Zebra Danio
Brachydanio rerio
NP_001007314
382
42180
I174
N
P
R
E
K
E
R
I
Q
N
A
G
G
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49596
356
39046
P149
S
V
V
G
E
A
R
P
L
S
F
D
H
K
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81716
355
39336
D148
P
D
S
W
P
L
E
D
G
P
H
S
D
F
T
Baker's Yeast
Sacchar. cerevisiae
P34221
468
51372
L248
T
S
Q
E
C
V
D
L
V
H
Y
G
I
S
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.6
99.5
97.2
N.A.
76.1
77
N.A.
62
77.2
78.9
67.6
N.A.
N.A.
N.A.
31.3
N.A.
Protein Similarity:
100
71.4
100
99.1
N.A.
79.9
79.3
N.A.
70.9
79.1
86.4
74.7
N.A.
N.A.
N.A.
46.9
N.A.
P-Site Identity:
100
13.3
93.3
93.3
N.A.
13.3
13.3
N.A.
13.3
13.3
6.6
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
26.6
26.6
N.A.
26.6
26.6
26.6
26.6
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
48
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
16
0
0
31
0
0
0
0
% A
% Cys:
0
0
0
0
8
31
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
16
8
0
0
8
8
8
0
0
% D
% Glu:
16
0
39
62
8
31
31
0
0
0
0
0
0
24
0
% E
% Phe:
8
0
0
0
0
0
0
16
0
0
8
0
0
8
0
% F
% Gly:
0
0
0
8
0
0
0
8
24
16
0
39
31
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
0
% H
% Ile:
0
8
8
0
16
0
0
31
8
0
0
0
8
16
0
% I
% Lys:
0
16
0
0
31
0
0
0
0
24
0
0
0
8
0
% K
% Leu:
0
0
16
8
24
8
0
8
8
0
0
0
24
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
0
% M
% Asn:
31
24
0
0
0
0
16
0
0
31
0
0
0
0
8
% N
% Pro:
8
31
0
0
8
0
0
8
0
8
0
0
0
0
8
% P
% Gln:
0
0
8
0
0
16
0
0
31
0
0
0
0
0
24
% Q
% Arg:
0
0
16
16
0
0
39
0
0
0
0
24
0
0
0
% R
% Ser:
31
8
8
0
0
0
0
0
0
8
39
8
0
47
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
8
8
0
0
8
0
0
31
0
0
24
0
0
54
% V
% Trp:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _